Adverse reactions to drugs are common, but everyone reacts differently. Almost any drug can cause an adverse reaction. It is the reaction from the unpleasant side effects such as nausea or mild and vomiting to anaphylaxis life threatening. Improper use of drugs is likely to cause allergies, sometimes only mild symptoms such as hives, inflammation, redness of the skin, but also can be serious as anaphylaxis, leading to death. A person may develop a rash or other reaction to certain medications, while others on the same drug may not have any adverse reactions.
The first time you take medicine, you cannot have problems. However, the immune system of your body may produce a substance (antibody) called IgE against that drug. IgE told your white blood cells to produce a chemical called histamine, causing your allergy symptoms.
Therefore, our writing will give you some basic information about these allergy diseases that may be caused from drugs.
- Quincke’s edema
- Serum sickness
- Atopic dermatitis
- Erythema multiforme
- Stevens-Johnson syndrome
- Penicillin allergy
Usually mild clinical manifestations and most of the initial cases of drug allergy. These drugs can cause hives, is more common antibiotics, vaccines, sera, anti-inflammatory, antipyretic… After taking drugs (quick 5-10 minute, delay can be a few days), the patient feels a burning sensation, itching, skin rash and swelling. Severe cases may have shortness of breath, abdominal pain, joint pain, dizziness, nausea, headache, fatigue, fever… It can appear on the part of the body or is spread over a large area. The rash usually very itchy and ranged in size from a few millimeters to the size of a hand.
- Acute urticaria often expresses increased rash, losing faster and faster as well reappear, changes in less than 3 weeks. Urticaria daily happenings, lasting more than 3 weeks are converted into chronic.
- Chronic urticaria – in rare cases, where the rash persists or travel for more than six weeks, often for many years
- A more rare type of urticaria, rash known as vasculitis, can cause blood vessels in the skin become inflamed. In this case, the weals lasted more than 24 hours, is more painful, and can leave a bruise.
2. Quincke’s edema:
This is in line angioneurotic (or angioedema), a form of localized swelling of the deeper layers of the skin and subcutaneous fat tissue. Angioneurotic consistent genetic (hereditary angioedema) is a form of hereditary angioedema. Consistent usually appear rapidly after administration in areas of thin skin, lips, neck, around eyes, abdomen, extremities, genitals… Sized to Quincke often large, sometimes by hand, if close eye makes eyes smaller, the lips swollen, deformed. The color matches the normal or slightly pinkish, sometimes in collaboration with urticaria. Where Quincke’s edema in the throat, larynx, the patient may choke; in the intestine, stomach pain stomach; in the brain causing headaches…
Agranulocytosis can trigger a minor infection to progress into severe ones. weak bacteria or tiny organisms (pathogens) are usually not harmful can suddenly become strong enough to attack your body.
It can appear after patients using drugs such as sulphonamides, penicillin high doses, streptomycin, chloramphenicol, pyramidon, analgin … typical clinical picture: sudden high fever, fatigue, health declined rapidly, rash, ribbon, hemorrhagic, necrotizing ulcerative oral mucosa, nose, throat, genitals, pneumonia, thrombophlebitis, dengue infection, easily lead to death.
The signs and symptoms of agranulocytosis that can include:
- fast heart beat
- low blood pressure
- skin abscess
Serum sickness is a reaction similar to an allergy. The immune system reacts to the protein-containing medicines are used to treat immune. Or it can react with the antiserum, the liquid part of blood that contains antibodies that give a man to help protect them against bacteria or toxic substances.
A catastrophe common allergy, mainly due to antibiotics such as penicillin, ampicillin, streptomycin… and some other drugs. The disease usually occurs on the second day to the 14th day after dosing with expression fatigue, loss of appetite, insomnia, nausea, joint pain, swollen lymph nodes more, high fever of 38-39 degrees C, hepatomegaly, well hives across the board. If detected in time and stop the medication, the symptoms will gradually end.
If you use drugs or pathogenic antiserum serum again in the future, the risk of having a similar reaction is very high.
- Anaphylaxis, security, threat response immediately
- Swelling of the face, arms and legs (edema)
Atopic dermatitis is very common worldwide and increasing in proportion. It affects men and women, and accounts for about 10% -20% of all referrals to dermatologists (doctors who specialize in the care and treatment of skin diseases). Atopic dermatitis usually occurs in infants and children, and its initial significant decrease with age.
The disease can be inherited and genetically determined. The patient’s skin can be “super sensitive” to many stimulants. Extremely dry skin can break down and cry outflow. If the itching can be controlled, rash (which is aggravated by scratching strong) can easily treat. In essence, the reaction type of eczema, the basic lesion is accompanied by vesicular rash, itching, skin edema and progressed in stages. Atopic dermatitis can occur quickly after a few hours, on average, after a few days, sometimes weeks after use or exposure to the drug.
Treatment of atopic dermatitis skin rehydration centers on the emollient such as lubrication and the use of topical steroid prudent to reduce inflammation and itching. Since secondary infections may aggravate the original, topical antibiotics or drink can also be sometimes indicated.
The culprit atopic dermatitis contact line is mainly topical medications, these drugs have the ability to diffuse into the environment (the fat antibiotics, anti-inflammatory, skin protection, exposed to the drug in drug production, nebulized antibiotics…). It can also occur due to use of the drug infusion, oral, nebulized.
Erythema systemic drugs as penicillin, ampicillin, streptomycin, sulphonamides, chloramphenicol, tetracycline, the sedative, analgesic, antipyretic… It occurs 2-3 days on average 6-7 days, sometimes 2-3 weeks after dosing. Patients feel hot flashes, tingling all over, fever, dyspepsia, rash body, white, scaly skin, the interstitial limbs can crack and drainage, sometimes multiple infections with pus.
The disease starts after a few days of dosing with the expression: mild fever, fatigue, joint pain, swollen lymph nodes, feeling hot body, the skin appears like papules papules round urticaria, floating flange edge higher, red slightly critical, the center of the papules slightly concave and wrinkled. In addition, there are vesicular rash, bullous, surrounded by a red halo; may be accompanied by mucosal lesions natural cavities, damage to internal organs (heart, liver, kidney…), relapse several times; Severe cases can cause death.
Stevens-Johnson syndrome (erythema multiforme have bullous):
Often caused by the antibiotics penicillin, ampicillin, streptomycin, tetracylin; the sulfamid slow, sedative, anti-inflammatory. After taking a few hours to 10-15 days, the patient fatigue, itching all over, feeling hot flashes, high fever, rash, bullous skin, mucosal ulceration and necrosis of the cavity itself course (mouth, eyes, nose, ears, anus, genitals, urinary) and may include liver and kidney damage, if severe can cause death.
Lyell Syndrome (target epidermal necrosis toxicity) is poisoning the most serious skin allergy medications such as slow sulfonamides, penicillin, ampicillin, streptomycin, tetracyline, analgin, Phenacetin… The course of several hours to several weeks after dosing. Patients tired daze, insomnia, fever, itching all over his body, the skin appears red patches, sometimes bleeding spots; a few days later, sometimes sooner, the epidermis separated from the organization skin, gently slide up to the patches, similar syndromes body burns. Patients may ulcer natural cavities, pneumonia, pleural, hepatitis, kidney disease status is often very severe, rapidly fatal.
Anaphylaxis is a severe allergic complications, deadly. Quite a number of drugs can cause anaphylaxis as antibiotics, vaccines, sera, nonsteroidal anti-inflammatory drugs, liver extract, some kind vitamin, anesthetics, iodine-containing contrast agents…
Flood chemicals released by your immune system during anaphylaxis may cause you to be shocked; a sudden drop in blood pressure and your airways to narrow, blocking breathing normally. Clinical anaphylaxis is quite diverse, can usually happens right after taking drugs a few seconds to 20-30 minutes, starting with the incredible feeling (numbness of the lips, tongue, anxiety, fear. ..). This is followed by the rapid appearance of symptoms such as shortness of breath, rapid pulse small, hypotension (sometimes not measured), tingling all over his body, abdominal pain, urinary, bowel incontinence, acute patients may comatose, choking, cardiac arrhythmias, cardiac arrest and died after a few minutes. Typically, these unpleasant symptoms occur at a location of the body. However, some people are more prone to severe anaphylactic reactions much.
Almost everyone knows someone says they are allergic to penicillin. Up to 10 percent of those who report an allergy to used class of antibiotics is widespread, making it the drug allergies most commonly reported. However, over time, the majority of those who have ever had a severe allergic reaction to penicillin lose sensitivity and can be handled safely with medications. Despite its effectiveness, some people steer clear of penicillin for fear of experiencing an allergic reaction to the drug.
Understand penicillin allergy is important for a variety of reasons. For some conditions, penicillin is the best (or only proven) treatments. Some patients need penicillin because they are allergic to the antibiotics. The symptoms may include any of the following:
- Rash (raised, very itchy spots that come and go over a period of time)
- Tissue swelling under the skin, usually around the face (also called edema)
- Throat secret
These symptoms require immediate attention at the nearest emergency room. Epinephrine, the treatment of choice, will be given in the context of emergency care, but also need to manage via autoinjector as soon as possible because patients have been prescribed and are wisely carry this device
If you frequently experience difficulty breathing or you hear a squeak or rattle in your chest when you breathe, you might have asthma is a chronic inflammatory disease and narrowing of the bronchial tubes, which allow lines air into and out of the lungs.
Asthma is a common long-term condition (especially if it was first developed in adulthood) that can cause coughing, wheezing, chest tightness and difficulty breathing. Sometimes, the symptoms of asthma can be gradual or sudden worsening. Asthma symptoms can usually be controlled and can be reversed with treatment, although some people with asthma can develop long lasting their airways narrow and more persistent problems. Moderate or severe asthma in children are more likely to persist or return later.
Sometimes the symptoms of asthma are mild and go away after treatment or at least equal to asthma medications. Other times, the symptoms continued to worsen. When these symptoms are more intense and / or more symptoms occur, you’re an asthma attack. also called asthma attacks or exacerbations flareups (ex-Zas-er-BA-shuns).
Although there is no treatment for asthma, with knowledge and current therapy, most people with asthma can manage the disease and live with it more easily. For successful treatment, thorough and ongoing, building strong partnerships with physicians and providers of health care other.
The article provides 10 diseases that drug allergy can cause, to help readers more knowledge to use it correctly. Drugs have a huge role to cure, but it can also become a cause of disease when not used properly. So everyone please keep in mind when buying medicines and read the user manual carefully before using.